Melatonin side effects long-term

Research shows that melatonin is safe and non-addictive for both short- and long-term use in adults ().

Additionally, despite concerns that supplementing with melatonin may decrease your body’s ability to produce it naturally, several studies show otherwise (, ).

However, because long-term studies on the effects of melatonin are limited to adults, it’s not currently recommended for children or adolescents ().

Some of the most commonly reported side effects associated with melatonin include nausea, headaches, dizziness and sleepiness ().

Melatonin may also interact with certain medications, including antidepressants, blood thinners and blood pressure medications (, 26, ).

If you’re taking any of these medications, talk to your doctor before taking melatonin to prevent adverse effects.

Summary

Studies show that melatonin is safe and associated with minimal side effects in adults but may interact with certain medications.

Melatonin may improve sleep, eye health, seasonal depression, HGH levels and GERD.

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