Macrobid in pregnancy 2nd trimester

Nitrofurantoin is commonly used to treat urinary tract infections (UTIs) in pregnant women. Comfort in selecting this antibiotic comes from its friendly FDA pregnancy category B rating and long history of safe and effective use.

However, the FDA pregnancy category ratings can be misleading because they are only meant to identify potential teratogens.

In the case of nitrofurantoin oral suspension (Furadantin), the prescribing information does not state that its use is contraindicated in pregnant patients at term (38 to 42 weeks of gestation), during labor and delivery, or when onset of labor is imminent.¹

This information comes from a population-based cohort study from Norway that was published in 2013.² Using the national Medical Birth Registry and Prescription Database, data from more than 180,000 births were analyzed to estimate whether exposure to nitrofurantoin is associated with increased incidence of negative pregnancy outcomes.

After comparing 1334 mothers who received nitrofurantoin during their pregnancy with 5800 mothers

is macrobid okay to take while pregnant

is nitrofurantoin okay to take while pregnant